She is of Algerian descent.
Active in dubbing, Azem was notably the French voice of Emma Watson until 2015. She is known for playing Dunk on Trop la Classe!, and Warrant Officer Sara Casanova on Research Unit (Section de recherches). Azem has also played Mireille on En passant pécho, and Nora in Gangsterdam. Manon can currently be seen playing the role of Lucie on the TF1 / Netflix series The Mantis(La Mante).